At this point you have the core pieces needed to branch out.
Good next directions include:
- Building cleaner logistics and power networks.
- Expanding into gantry automation and machine-frame based farms.
- Investing in multiblocks and addons.
- Pushing toward nuclear reactors or the particle accelerator.
- Starting cybernetic augmentation research once your resource flow is stable.
Explore the rest of the manual, pick a direction, and start specializing your factory.